Acetaminophen, Dextromethorphan, and Phenylephrine Overview
(a seet a MIN oh fen, deks troe meth OR fan, & fen il EF rin)
Created: 2007-07-13 10:31:50.0
Modified: 2010-03-09 08:27:47.0
Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.
• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
How does it work?
• Acetaminophen blocks production and release of chemicals that cause pain.
• Dextromethorphan affects the cough center in the brain.
• Phenylephrine shrinks swollen nasal tissue and opens up passages.
How is it best taken?
• Do not take more than prescribed amount. Liver damage can occur.
• Take this medicine with or without food. Take with food if it causes an upset stomach.
• Swallow whole. Do not chew, break, or crush.
• A liquid (solution) is available if you cannot swallow pills.
• Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after medicine is given.
• Drink plenty of noncaffeine-containing liquid unless told to drink less liquid by healthcare provider.
How should I store this medicine?
• Store at room temperature.
• Protect from light.
• Protect capsules from moisture. Do not store in a bathroom or kitchen.
Analgesic, Miscellaneous; Antitussive; Decongestant
Reasons not to take this medicine
• If you have an allergy to acetaminophen, dextromethorphan, phenylephrine, or any other part of this medicine.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
• If you have taken isocarboxazid, phenelzine, or tranylcypromine in the last 14 days. Monoamine oxidase inhibitors (eg, isocarboxazid, phenelzine, and tranylcypromine) must be stopped 14 days before this medicine is started. Taking the two together could cause dangerously high blood pressure.
U.S. Brand Names
Alka-Seltzer Plus® Day Cold [OTC]; Comtrex® Maximum Strength, Non-Drowsy Cold & Cough Relief [OTC]; Mapap® Multi-Symptom Cold [OTC]; Theraflu® Daytime Severe Cold & Cough [OTC]; Theraflu® Warming Relief Daytime Severe Cold & Cough [OTC]; Tylenol® Cold Head Congestion Daytime [OTC]; Tylenol® Cold Multi-Symptom Daytime [OTC]; Vicks® DayQuil® Cold/Flu Multi-Symptom [OTC]
What do I do if I miss a dose? (does not apply to patients in the hospital)
• Take a missed dose as soon as possible.
• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
• Do not take a double dose or extra doses.
• Many times this medicine is taken on an as needed basis.
What key warnings should I know about before taking this medicine?
• Talk with healthcare provider before giving this medicine to a child. Check all of your child's medicines, including over-the-counter, with healthcare provider.
• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.
What should I monitor?
• Change in condition being treated. Is it better, worse, or about the same?
• Dry mouth may cause an increase in cavities. Take good care of your teeth. See a dentist regularly.