ADHD and DMAE (2-Dimethylaminoethanol)
Effect of DMAE (2-Dimethylaminoethanol) on ADHD
DMAE (2-dimethylaminoethanol) is a chemical that has been used to treat a number of conditions affecting the brain and central nervous system. Like other such treatments, it is thought to work by increasing production of the neurotransmitter acetylcholine.
Research Evidence on DMAE (2-Dimethylaminoethanol)
There is some evidence that the supplement DMAE (2-Dimethylaminoethanol) may be helpful for ADD, according to studies performed in the 1970s. Two such studies were reported in a review article.1 Fifty children aged 6 to 12 years who had been diagnosed with hyperkinesia (which would likely be ADHD in today's terms) participated in a double-blind study comparing DMAE to placebo. The dose was increased from 300 mg daily to 500 mg daily by the third week and continued for 10 weeks. Evaluations revealed statistically significant test score improvements in the treatment group compared to the placebo group.
Another double-blind study compared DMAE with both Ritalin and placebo in 74 children with "learning disabilities. 1 (It appears that today, the participants would have been given a diagnosis of ADD). The study found significant test score improvement for both treatment groups over a 10-week period.
- 2-Dimethylaminoethanol (deanol): a brief review of its clinical efficacy and postulated mechanism of action. Curr Ther Res Clin Exp. 1974;16:1238-1242.