Alendronate and Cholecalciferol
What is it? Overview Usage Side Effects and Warnings

Alendronate and Cholecalciferol Overview

Written by FoundHealth.

(a LEN droe nate & kole e kal SI fer ole)

U.S. Brand Names

Fosamax Plus D™

Canadian Brand Names


Mexican Brand Names

Fosamax Plus

Pharmacologic Category

Bisphosphonate Derivative; Vitamin D Analog

Reasons not to take this medicine

• If you have an allergy to alendronate, vitamin D, cholecalciferol, or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you have any of the following conditions: Abnormal esophagus (swallowing tube), low calcium levels, or trouble swallowing.

• If you are unable to stand or sit up for half an hour.

• If you have a malabsorption syndrome or too much vitamin D or calcium in your system.

How does it work?

• Alendronate reduces bone destruction.

• Cholecalciferol acts as a hormone to control calcium absorption in the body.

How is it best taken?

• Take this medicine on an empty stomach before breakfast.

• Take this medicine with a full glass of water at least 30 minutes before the first food, drink, or medicine of the day.

• Take this medicine with plain water only. Avoid taking with mineral water or other drinks.

• Swallow tablet whole. Do not chew, break, or crush.

• Do not lie down for at least 30 minutes after taking this medicine. This prevents irritation to the esophagus (swallowing tube).

• This medicine works best when used with calcium/vitamin D supplements and weight-bearing exercises like walking or physical therapy.

• Follow diet plan and exercise program as recommended by healthcare provider.

What do I do if I miss a dose? (does not apply to patients in the hospital)

• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

• Do not change dose or stop medicine. Talk with healthcare provider.

What should I monitor?

• Change in condition being treated. Is it better, worse, or about the same?

• Bone density test.

• Take good care of your teeth. See a dentist regularly.

• Follow up with healthcare provider.

How should I store this medicine?

• Store at room temperature.

• Protect from light.

• Protect from moisture. Do not store in a bathroom or kitchen.

General statements

• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

Created: 2005-05-04 10:56:40.0

Modified: 2010-03-09 08:26:50.0

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