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Allergic Rhinitis and Leukotriene Inhibitors

Read more about Leukotriene Inhibitors.


Like the mast cell stabilizers, leukotrine inhibitors are used to prevent some of the symptoms of allergic rhinitis. Montelukast (Singulair) is a common leukotrine inhibitor.

Effect of Leukotriene Inhibitors on Allergic Rhinitis

Singulair works by decreasing how many leukotrienes (chemicals) the body creates in response to an allergen, thereby preventing symptoms from developing.

Side Effects and Warnings

Possible side effects of leukotrine inhibitors include:

  • Flu-like symptoms
  • Nervousness
  • Headache and stomach ache
  • Nausea and vomiting
  • Nasal congestion

Note: The US Food and Drug Administration (FDA) is investigating to see if there is a link between taking this medication and having suicidal thoughts. If you are taking Singulair, do not stop right way. Talk to your doctor first.