Antihemophilic Factor (Recombinant):
What is it?

Antihemophilic Factor (Recombinant):
How is it Used?

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Antihemophilic Factor (Recombinant) Overview


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Created: 2005-04-07 16:18:46.0

Modified: 2010-03-09 08:19:12.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

Canadian Brand Names

Advate; Helixate® FS; Kogenate®; Kogenate® FS; Recombinate; ReFacto®

General statements

• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

How does it work?

• Antihemophilic factor (recombinant) replaces the proper proteins to prevent bleeding.

How is it best taken?

• This medicine is given as a shot into a vein.

• This medicine can be given at home.

• Your healthcare provider may teach you how to give the shot.

• Wash hands before and after use.

• Throw away needles in needle/sharp disposal box and return box to healthcare provider when full.

How should I store this medicine?

• Usually, this medicine will be given to you in a healthcare setting. You will not store it at home.

• If given at home, may store unopened vials at room temperature or in a refrigerator. Do not freeze.

• If stored at room temperature, throw away any unused Advate vials after 6 months.

• If stored at room temperature, throw away any unused Helixate® FS, Kogenate® FS, Recombinate™, ReFacto®, or Xyntha™ vials after 3 months.

• Protect from light.

Mexican Brand Names

Koate DVI; Novo Nordsk; Novoseven

Pharmacologic Category

Antihemophilic Agent

Reasons not to take this medicine

• If you have an allergy to antihemophilic factor (recombinant), mice, hamsters, pigs, or any part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

U.S. Brand Names

Advate; Helixate® FS; Kogenate® FS; Recombinate; ReFacto® [DSC]; Xyntha™

What should I monitor?

• Change in condition being treated. Is it better, worse, or about the same?

• Follow up with healthcare provider.