Back Pain and Alpha-2-Adrenergic Agonists
Effect of Alpha-2-Adrenergic Agonists on Back Pain
There are alpha-2-Adrenergic Agonists that have shown to to relieve pain, namely: Tizanidine (Zanaflex) and Clonidine (Catapres). This type of agents have long been used for treating various health problems including hypertension and withdrawal from alcohol or other substances.
Effect of Tizanidine on Back Pain
Tizanidine promotes back pain relief by blocking the transmission of nerve impulses to the brain. It is also to used treat muscle stiffness or rigidness by temporarily relaxing the muscle tone.
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Effect of Clonidine on Back Pain
Clonidine is thought to relieve back pain by inhibiting pain signal transmission in spinal segments where the drug is introduced. Clonidine decreases the body's release of adrenaline and other...
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