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Capsaicin creams commonly cause an unpleasant burning sensation when they are first applied; this sensation disappears over subsequent days as treatment is continued.
As a commonly used food, cayenne is generally recognized as safe. Contrary to some reports, cayenne does not appear to aggravate stomach ulcers . 1
Interactions You Should Know About
If you are taking:
- The asthma drug theophylline : Cayenne might increase the amount you absorb, possibly leading to toxic levels. 2
- Nonsteroidal anti-inflammatory drugs : Cayenne might protect your stomach from damage.
- Graham DY, Smith JL, Opekun AR. Spicy food and the stomach. Evaluation by videoendoscopy. JAMA. 260(23):3473-5.
- Bouraoui A, Toumi A, Mustapha HB, et al. Effects of capsicum fruit on theophylline absorption and bioavailability in rabbits. Drug Nutr Interact. 1998;5:345-350.