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Chondroitin generally does not cause much in the way of side effects, besides occasional mild digestive distress.
However, there is one case report of an exacerbation of asthma caused by use of a glucosamine-chondroitin product.210
In addition, there are theoretical concerns that chondroitin might have a mild blood-thinning effect, based on its chemical similarity to the anticoagulant drug heparin. Reassuringly, there are no case reports of any problems relating to this, and studies suggest that chondroitin has at most a mild anticoagulant effect.36 Nonetheless, prudence suggests that, based on these findings, chondroitin should not be combined with blood-thinning drugs, such as warfarin (Coumadin), heparin, and aspirin, except under physician supervision. In addition,...