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According to studies performed primarily in the former Soviet Union, Eleutherococcusappears to present a low order of toxicity in both the short- and long-term. Human trials have not resulted in any significant side effects. 1 Safety in pregnant or nursing women, young children, or people with severe liver or kidney disease is not known.
One report suggests that Eleutherococcusmay alter the results of a test for the medication digoxin. 2 However, it is not clear whether it was the Eleutherococcusor a contaminant (eg, digoxin mixed with the herb) that caused these problems.
Interactions You Should Know About
If you are taking:
- Digoxin : Eleutherococcus may interfere with blood tests designed to measure digoxin level.
- Farnsworth NR, Kinghorn AD, Soejarto DD, et al. Siberian ginseng ( Eleutherococcus senticosus ): current status as an adaptogen. Econ Med Plant Res. 1985;1:156-215.
- McRae S. Elevated serum digoxin levels in a patient taking digoxin and Siberian ginseng. CMAJ. 1996;155:293-295.