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Gout and Nonsteroidal Anti-inflammatory Agents (NSAIDs)

Written by sshowalter.

Effect of Nonsteroidal Anti-inflammatory Agents (NSAIDs) on Gout

Common names include:

  • Ibuprofen (Apo-Ibuprofen)
  • Indomethacin (Indocin)
  • Naproxen (Aleve)
  • Diclofenac (Cataflam)

NSAIDs are given to treat the pain, inflammation, and swelling caused by gout attacks. They can be purchased over-the-counter or your doctor may prescribe a higher dosage. They work by decreasing prostaglandins, hormones that produce inflammation and pain. The medicine may also be taken in smaller doses to help prevent attacks in patients with recurrent gout attacks. NSAIDs are given in tablet, capsule, or liquid form. They should be taken at the same time (or times) each day and should be taken with food or liquid to help avoid stomach upset.

Read more details about Nonsteroidal Anti-inflammatory Agents (NSAIDs).

Drinking alcoholic beverages or taking other NSAIDs while you are already using an NSAID can increase your risk of side effects. Always take NSAIDs with food to decrease the chance of stomach irritation.

Possible side effects include:

  • Stomach upset
  • Stomach ulcers
  • Kidney damage
  • Liver inflammation
  • Confusion, dizziness, lightheadedness
  • Severe allergic reaction (hives, difficulty breathing, swelling around the eyes)
  • Increased risk of bleeding – Always inform your healthcare providers that you are taking an NSAID before having any medical or dental procedures or surgeries.

Take special care with NSAIDs if you have had an ulcer or gastritis, as they can irritate these conditions. Tell your doctor if you have a stomach condition before you start taking any of these medications.

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