Lomustine Side Effects and Warnings

What are the precautions when taking this medicine?

• If you have kidney disease, talk with healthcare provider.

• If you have liver disease, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.

• Talk with healthcare provider before using aspirin, aspirin-containing products, other pain medicines, blood thinners, garlic, ginseng, ginkgo, or vitamin E.

• Use birth control that you can trust to prevent pregnancy while taking this medicine.

What are some possible side effects of this medicine?

• Risk of infection. Avoid people with infections, colds, or flu.

• Anemia, low white blood cell count, and low platelet count. Medicine may need to be stopped.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. You may be given a medicine to prevent these symptoms.

• Lung damage can occur.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.

• Difficulty breathing.

• Severe belly pain.

• Significant change in thinking clearly and logically.

• Severe nausea or vomiting.

• Severe diarrhea.

• Not able to eat.

• Unusual bruising or bleeding.

• Swelling of legs or belly.

• Dark urine or yellow skin or eyes.

• Unable to pass urine.

• Feeling extremely tired or weak.

• Severe skin irritation.

• Any rash.

• No improvement in condition or feeling worse.