What is it? Overview Usage Side Effects and Warnings

What is Mesoglycan?

Mesoglycan is a type of substance found in many tissues in the body, including the joints, intestines, and the lining of blood vessels. Chemically, mesoglycan is related to the blood-thinning drug heparin and the supplement chondroitin . Unlike chondroitin, mesoglycan is primarily used to treat diseases of blood vessels. Preliminary evidence suggests that mesoglycan may be helpful for atherosclerosis, varicose veins, phlebitis, and hemorrhoids.

Most proposed uses of mesoglycan involve diseases of blood vessels. For example, evidence suggests that mesoglycan may slow the development of hardening of the arteries , perhaps by lowering cholesterol levels , "thinning" the blood, or through other effects. 1 People with severe hardening of the arteries sometimes develop blockage in the arteries of the legs, a condition called intermittent claudication . This condition limits the ability to walk by causing intense, crampy pain after walking a relatively short distance. There is some evidence that mesoglycan may help. 2 The conditions just discussed involve arteries. Mesoglycan may also be useful for various diseases of the veins, including varicose veins/venous insufficiency , hemorrhoids , and phlebitis . 3 One study...

Safety Issues

Mesoglycan is essentially ground-up pig intestines and is believed to be safe, even if taken in large quantities. However, because mesoglycan appears to decrease blood clotting, it should not be combined with prescription blood thinners such as warfarin (Coumadin), clopidogrel (Plavix), ticlopidine (Ticlid), pentoxifylline (Trental), or heparin, or drugs in the aspirin family. Maximum safe dosages for young children, pregnant or nursing women, or those with severe liver or kidney disease have not been determined.

Interactions You Should Know About

If you are taking drugs that decrease blood clotting, such as warfarin (Coumadin) , heparin , clopidogrel (Plavix), ticlopidine (Ticlid), pentoxifylline (Trental) , or aspirin , do not use mesoglycan except under...