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Osteoarthritis and Cyclooxygenase-2 or COX-2 Inhibitors

Read more about Cyclooxygenase-2 or COX-2 Inhibitors.

Effect of Cyclooxygenase-2 or COX-2 Inhibitors on Osteoarthritis

COX-2 inhibitors work in a way similar to NSAIDs, helping to decrease inflammation, swelling, and joint pain. In addition, they have the benefit of causing less stomach irritation. In particular, COX-2 inhibitors cause far fewer stomach ulcers than do NSAIDs.

Most commonly prescribed COX-2 Inhibitors for Osteoarthritis:

  • Celecoxib (Celebrex)
  • Meloxicam (Mobic)

Side Effects and Warnings

Drinking alcoholic beverages or taking NSAIDs while you are using a COX-2 inhibitor can increase your risk of side effects.

Possible side effects include:

  • Liver inflammation
  • Confusion
  • Severe allergic reaction ( hives, difficulty breathing, swelling around the eyes)
  • Stomach upset
  • Heart attack
  • Stroke

References

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