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Since severe allergic reactions are common with this medicine, a corticosteroid and an antihistamine are given before the injection of pegloticase.
Other possible side effects include:
- Flare-up of gout
- Nausea and vomiting
- Bruise at the injection site
- Nasal irritation
- Chest pain
The medicine has not been studied in people who have congestive heart failure. Consult your practitioner before going on this or any other medication.