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Because it is used as food in Asia, reishi is generally regarded as safe. One small study evaluating the safety of reishi when taken at a dose of 2 g daily for 10 days failed to find any evidence of ill effects. 1 However, another study found indications that reishi impairs blood clotting. 2 For this reason, prudence suggests that individuals with bleeding problems should avoid reishi; the herb should also be avoided in the period just before and after surgery or labor and delivery. Furthermore, individuals taking medications that impair blood clotting, such as aspirin, warfarin (Coumadin), heparin, clopidogrel (Plavix ), pentoxifylline (Trental ), or ticlopidine (Ticlid), should only use reishi under a doctor’s supervision.
Safety in young children, pregnant or nursing women, or those with severe liver or kidney disease has not been established.
Interactions You Should Know About
If you are taking blood-thinning medications, such as aspirin , warfarin ( Coumadin ), heparin , clopidogrel ( Plavix ), pentoxifylline (Trental), or ticlopidine (Ticlid), use reishi only under a doctor's supervision.
- Wicks SM, Tong R, Wang CZ, et al. Safety and tolerability of Ganoderma lucidum in healthy subjects: a double-blind randomized placebo-controlled trial. Am J Chin Med. 2007;35:407-414.
- Su C, Shiao M, Wang C. Potentiation of ganodermic acid S on prostaglandin E(1)-induced cyclic AMP elevation in human platelets. Thromb Res. 99(2):135-45.