SSRIs
What is it? Overview Usage Side Effects and Warnings
Answers

What are SSRIs?

Selective serotonin reuptake inhibitors (SSRIs) are a class of pharmacological antidepressants. They are currently the most popular class of antidepressant medications because of their relative safety in comparison to monoamine oxidase inhibitors (MAOIs) and tricyclics (TCAs).

Possible side effects of SSRIs include:

  • Drowsiness
  • Dryness of mouth
  • Blurred vision
  • Nausea
  • Dizziness
  • Difficulty sleeping
  • Sexual dysfunction
  • Risk of severe mood and behavior changes
  • Suicidal thoughts and actions

Gastrointestinal upset is the most common side effect that users experience. These include nausea, diarrhea, and cramping. It is commonly recommended that users take SSRIs with food and an antacid or antiemetic for the first 2-3 weeks of treatment.

SSRIs also activate the central nervous system, which can result in agitation, anxiety, restlessness, and insomnia.

FDA issued a warning that combining an SSRI with one of the commonly-used "triptan" medications for migraine headaches can cause serious side effects...

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Possible side effects include:

  • Nausea
  • Diarrhea
  • Insomnia
  • Sexual dysfunction
  • Headache
  • Risk of severe mood and behavior changes, including suicidal thoughts in some patients (Young adults may be at a higher risk for this side effect.)
 
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