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Sulfadoxine and Pyrimethamine
What is it? Overview Usage Side Effects and Warnings
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Sulfadoxine and Pyrimethamine Side Effects and Warnings

Written by FoundHealth.

What are the precautions when taking this medicine?

• If you have kidney disease, talk with healthcare provider.

• If you have liver disease, talk with healthcare provider.

• If you have seizures, talk with healthcare provider.

• Other protective measures are needed along with this medicine including using screens, bednetting, insect repellent (10% to 35% DEET), and permethrin spray on clothing and nets. Avoid spraying most insect repellents on children. Decrease evening and night-time outdoor activity.

• Be careful if you have G6PD deficiency. Anemia may occur.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• You can get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen; wear protective clothing and eyewear.

• If you are pregnant or planning on getting pregnant, talk with healthcare provider. You may need even higher doses of folic acid.

• Pregnant females traveling to malaria infested areas should discuss the risks with a healthcare provider first.

What are some possible side effects of this medicine?

• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.

• Headache.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Belly pain.

• Anemia and low platelet count can rarely occur.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.

• Fever that occurs while in or after return from the malaria area.

• Severe dizziness or passing out.

• Severe nausea or vomiting.

• Dark urine or yellow skin or eyes.

• Unusual bruising or bleeding.

• Feeling extremely tired or weak.

• Any rash.

• No improvement in condition or feeling worse.

 
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