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Sulforaphane is a chemical found in broccoli sprouts, as well as other cabbage-family vegetables such as broccoli, Brussels sprouts, cabbage, cauliflower, and kale. Some evidence hints that sulforaphane might help prevent cancer.
Numerous observational studies have found that a high consumption of vegetables in the cabbage family is associated with a reduced risk of cancer, especially breast, prostate, lung, stomach, colon, and rectal cancer. 1 On this basis, scientists have looked for anticancer substances in these foods. Sulforaphane is one such candidate substance ( indole-3-carbinol , I3C, is another). In test-tube and animal studies , sulforaphane exhibits properties that suggest it could indeed help prevent many forms of cancer. 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 However, it is a long way from such studies to reliable evidence of benefit. Observational studies are notoriously poor guides to treatment,...
No major adverse effects have been reported with sulforaphane supplements, but comprehensive studies have not been performed. Maximum safe doses in young children, pregnant or nursing women, or people with severe liver or kidney disease are not known.
NOTE: Sulforaphane has shown the potential for interacting with numerous medications. 23 For this reason, we recommend that people taking any oral or injected medication that is critical to their health or well-being avoid using sulforaphane supplements until more is known.
Interactions You Should Know About
If you are taking any medication that is critical to your health, do not take sulforaphane supplements except under physician supervision.