Insulin resistance is the state in which the body resists its own insulin. It is caused by a chemical issue on the cells outer surface or it can be from the misshapen cells surface due to weight gain. This resistance is usually seen after eating when digestion of food causes glucose levels to rise beyond what the body can handle. As a result, glucose levels remain high for a number of hours after meals. Very often, particularly in pre-diabetes, glucose levels return to normal if food hasn’t been eaten for a number of hours including the fasting blood glucose.