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Riboflavin, also known as vitamin B 2 , is an essential nutrient required for life. This vitamin works with two enzymes critical to the body's production of adenosine triphosphate (ATP)—its main energy source. Vitamin B 2 is also used to process amino acids and fats and to activate vitamin B 6 and folate.
Preliminary evidence suggests that riboflavin supplements may offer benefits for two illnesses: migraine headaches and cataracts.
Preliminary evidence suggests that riboflavin supplements taken at high dosages may reduce the frequency of migraine headaches . 1 One very large study suggests that riboflavin at nutritional doses may be helpful for cataracts , but in this study it was combined with another B vitamin—niacin ( vitamin B 3 )—so it's hard to say which vitamin was responsible for the effect. 2 Riboflavin has also been proposed as a treatment for sickle-cell anemia , 3 HIV infection, 4 and as a performance enhancer for athletes, but there is no real evidence that it is effective for these uses.
Riboflavin seems to be an extremely safe supplement.