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Linezolid
What is it? Overview Usage Side Effects and Warnings
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Linezolid Overview

Written by FoundHealth.

(li NE zoh lid)

U.S. Brand Names

Zyvox®

Canadian Brand Names

Zyvoxam®

Mexican Brand Names

Zyvoxam

Pharmacologic Category

Antibiotic, Oxazolidinone

What key warnings should I know about before taking this medicine?

• Linezolid may cause anemia, low white blood cell counts, low platelet counts, or may decrease production of all cells made in the bone marrow. Complete blood counts should be done weekly while on this medicine.

• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.

Reasons not to take this medicine

• If you have an allergy to linezolid or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you have uncontrolled high blood pressure.

• If you have taken isocarboxazid, phenelzine, or tranylcypromine in the last 14 days. Monoamine oxidase inhibitors (eg, isocarboxazid, phenelzine, and tranylcypromine) must be stopped 14 days before this medicine is started. Taking the two together could cause dangerously high blood pressure.

How does it work?

• Linezolid works to injure the bacteria and fight the infection.

How is it best taken?

• To gain the most benefit, do not miss doses.

• Use prescription as directed, even if feeling better.

• Take this medicine with or without food. Take with food if it causes an upset stomach.

• Follow diet instructions. Certain foods and drinks taken with this medicine can cause very dangerous reactions such as sudden high blood pressure. To prevent these problems, get a list of foods to avoid from a nutritionist.

• Avoid eating aged cheeses and meats, soy sauce, soy bean including paste, Miso soup, Italian green beans (fava beans), snowpea or broad bean pods, sauerkraut, kimchee, concentrated yeast extracts (Marmite), red or white wine, and beer including alcohol-free beer.

• If medicine is stopped, follow diet for at least 2 more weeks.

• A liquid (suspension) is available if you cannot swallow pills. Gently mix before use. Do not shake.

• Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after medicine is given.

Injection:

• This medicine is given as a shot into a vein over a period of time.

What do I do if I miss a dose? (does not apply to patients in the hospital)

• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

What should I monitor?

• Change in condition being treated. Is it better, worse, or about the same?

• Check blood pressure and heart rate regularly if you have heart disease.

• Check blood work regularly. Talk with healthcare provider.

How should I store this medicine?

• Store at room temperature.

• Protect from light.

• Protect tablets from moisture. Do not store in a bathroom or kitchen.

• Store liquid (suspension) at room temperature. Throw away any unused portion after 3 weeks.

• Follow directions for storage of injection. Talk with healthcare provider.

General statements

• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

Created: 2006-10-13 13:39:53.0

Modified: 2010-05-05 15:41:31.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

 
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