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ADHD and Non-stimulants

Written by green crane, Molly Hartle.

In roughly 20 percent of the cases of people with ADHD, stimulants don’t work. This is the main reason why some individuals will turn to a non-stimulant instead. Individuals may also choose a non-stimulant due to the adverse side effects of stimulants. That said, all medications have side effects; non-stimulants are no exception. Finally, a third reason why individuals may choose a non-stimulant is to treat an associated disorder at the same time. For the purpose of treating ADHD, non-stimulants are grouped under the following types: antidepressants, antihypertensives, mood stabilizers and neuroleptic drugs. A fifth type, unceremoniously known as simply “non-stimulant,” is used to categorize the selective norepinephrine reuptake inhibitor atomoxetine.

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Effect of Atomoxetine on ADHD

Atomoxetine is a selective norepinephrine reuptake inhibitor. This means that is blocks the reabsorption of norepinephrine, increasing its overall availability. Unlike stimulants that work on the...

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Effect of Antidepressants on ADHD

Read more about ADHD and Antidepressants.

Effect of Antihypertensives on ADHD

Antihypertensives selectively stimulate the receptors associated with the neurotransmitters norepinephrine and epinephrine in the brain. The result is an increase in an individual’s ability to...

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Effect of Mood Stabilizers on ADHD

Mood stabilizers work in a variety of ways. Lithium, for example, increases the amount of serotonin—a known mood stabilizer in the brain. Carbamazepine, volproic acid, and lamotrigine, on the other...

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Effect of Narcoleptic drugs on ADHD

A prohistamine, modafinil promotes wakefulness by stimulating the histamine in the brain. Specifically, modafinil helps to promote frontal-lobe functions such as decision-making, organization, time...

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