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Atovaquone and Proguanil
What is it? Overview Usage Side Effects and Warnings

Atovaquone and Proguanil Overview

Written by FoundHealth.

(a TOE va kwone & pro GWA nil)

U.S. Brand Names


Canadian Brand Names

Malarone®; Malarone® Pediatric

Pharmacologic Category

Antimalarial Agent

What key warnings should I know about before taking this medicine?

• This medicine does not mix well with some medicines. Serious reactions may occur. Check all medicines with healthcare provider.

Reasons not to take this medicine

• If you have an allergy to atovaquone, proguanil, or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you are using this medicine to prevent malaria and have severe kidney disease.

How does it work?

• Atovaquone and proguanil work to injure the parasite and fight the infection.

How is it best taken?

• This medicine should be started before travel to the high risk area. Continue use after leaving the area.

• To gain the most benefit, do not miss doses.

• Use prescription as directed, to prevent malaria.

• Take this medicine at a similar time of day.

• Take this medicine with food.

• If you vomit within 1 hour of taking this medicine, take another dose.

• May crush tablet and mix with milk.

What do I do if I miss a dose? (does not apply to patients in the hospital)

• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

• Do not change dose or stop medicine. Talk with healthcare provider.

What should I monitor?

• Change in condition being treated. Is it better, worse, or about the same?

How should I store this medicine?

• Store at room temperature.

• Protect from moisture. Do not store in a bathroom or kitchen.

General statements

• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

Created: 2005-04-07 16:19:54.0

Modified: 2010-03-09 08:21:59.0

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