Bevacizumab Side Effects and Warnings

What are the precautions when taking this medicine?

Injection:

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• If you have heart disease, talk with healthcare provider.

• If you have had blood clots, talk with healthcare provider.

• If you have high blood pressure, talk with healthcare provider.

• Tell dentists, surgeons, and other healthcare providers that you use this medicine.

• You may bleed more easily. Be careful. Avoid injury. Use soft toothbrush, electric razor.

• Talk with healthcare provider before using other: aspirin, aspirin-containing products, blood thinners, garlic, ginseng, ginkgo, ibuprofen or like products, pain medicines, or vitamin E.

• Use birth control that you can trust to prevent pregnancy.

Eye:

• If you have glaucoma, talk with healthcare provider.

What are some possible side effects of this medicine?

Injection:

• Bleeding problems.

• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.

• Headache.

• Belly pain.

• Back pain.

• High or low blood pressure.

• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Diarrhea.

• Feeling tired or weak.

• Not hungry.

• Delayed wound healing.

• Skin irritation.

Eye:

• Increased eye pressure.

• Eye infection.

• Eye irritation.

• Blurred vision. Use caution when driving or doing other tasks that require you to have clear vision.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Severe dizziness or passing out.

• Difficulty breathing.

• Swelling of legs or belly.

• Severe headache.

• Seizures.

• Significant change in thinking clearly and logically.

• Sudden change in vision, eye pain, or irritation.

• Severe nausea or vomiting.

• Severe constipation.

• Severe belly pain.

• Severe diarrhea.

• Numbness or tingling of hands or feet.

• Skin wound that will not heal.

• Cloudy or pink-red urine.

• Unusual bruising or bleeding.

• Any rash.

• No improvement in condition or feeling worse.