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Blue flag has not undergone any meaningful scientific study. High doses of blue flag are known to cause severe gastrointestinal upset, including nausea, vomiting, and diarrhea, and related species are known to be toxic. 1 The fresh herb can irritate the mouth and stomach. Blue flag is considered unsafe for use by pregnant or nursing women and young children.
- Newall C., Anderson L, Phillipson J. Herbal Medicines, A Guide for Healthcare Professionals. London:Pharmaceutical Press; 1996.