Capecitabine Side Effects and Warnings

What are the precautions when taking this medicine?

• If you are 80 or older, use this medicine with caution. You could have more side effects.

• If you have heart disease, talk with healthcare provider.

• If you have liver disease, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.

• Use birth control that you can trust to prevent pregnancy while taking this medicine.

What are some possible side effects of this medicine?

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Diarrhea.

• Swelling.

• Feeling tired or weak.

• Belly pain.

• Eye irritation.

• Skin irritation.

• Mouth irritation. Frequent mouth care with a soft toothbrush or cotton swabs and rinsing mouth may help.

• Anemia, low white blood cell count, and low platelet count.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.

• Difficulty breathing.

• Severe nausea or vomiting.

• Severe diarrhea.

• Numbness or tingling of hands or feet.

• Pain and irritation of feet or hands.

• Unusual bruising or bleeding.

• Severe skin irritation.

• Severe mouth irritation.

• Sudden change in vision, eye pain, or irritation.

• Any rash.

• No improvement in condition or feeling worse.