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Alteplase Contributions by FoundHealth

Article Revisions

Edited Alteplase Overview: Overview 14 years ago

(AL te plase)

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Activase®; Cathflo® Activase®

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Activase® rt-PA; Cathflo® Activase®

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Actilyse

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Thrombolytic Agent

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• If you have an allergy to alteplase or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you have any of the following conditions: Aneurysm, arteriovenous malformations, bleeding problems, brain tumor, injury to the brain or spine in the last 2 months, stroke, surgery on the brain or spine in the last 2 months, or uncontrolled high blood pressure.

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• Alteplase dissolves blood clots.

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• This medicine is given as a shot into a vein.

• This medicine is given as a shot into the catheter.

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• Call healthcare provider for instructions.

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• Change in condition being treated. Is it better, worse, or about the same?

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• This medicine will be given to you in a healthcare setting. You will not store it at home.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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Edited Alteplase Overview: 14 years ago

Created: 2005-04-07 16:16:40.0

Modified: 2010-03-09 08:17:38.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• This medicine is used to prevent muscle damage to the heart during a heart attack.

• This medicine is used to clear blood clots out of catheters.

• This medicine is used to treat blood clots.

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What are the precautions when taking this medicine?

• If you have had any recent surgery or dental procedures, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Use caution to prevent injury and avoid falls or accidents.

• Tell healthcare provider if you are pregnant or plan on getting pregnant.

• Tell healthcare provider if you are breast-feeding.

What are some possible side effects of this medicine?

• Serious bleeding can rarely occur.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Chest pain or pressure.

• Unusual bruising or bleeding.

• Significant change in thinking clearly and logically.

• Severe headache.

• Severe back pain.

• Severe belly pain.

• Feeling extremely tired or weak.

• Any rash.

• No improvement in condition or feeling worse.

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