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Arsenic Trioxide Contributions by FoundHealth

Article Revisions

(AR se nik tri OKS id)

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Trisenox®

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Antineoplastic Agent, Miscellaneous

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• Dangerous, fast heartbeats can occur. Tell healthcare provider if you have a history of fast heartbeats, kidney failure, low potassium or magnesium levels, or lung failure. Check all medicines with healthcare provider.

• This medicine can cause a condition called retinoic-acid-APL syndrome. Severe problems can occur in some patients who develop this condition. Call healthcare provider right away if you have fever, difficulty breathing, or weight gain.

• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.

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• If you have an allergy to arsenic trioxide or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you are pregnant or may be pregnant.

• If you are breast-feeding.

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• Arsenic trioxide injures cancer cells causing their death.

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• This medicine is given as a shot into a vein over a period of time.

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• Call healthcare provider for appointment.

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• You will be monitored closely by healthcare provider.

• Change in condition being treated. Is it better, worse, or about the same?

• Check blood work regularly. Talk with healthcare provider.

• Follow up with healthcare provider.

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• The injection will be given to you in a healthcare setting. You will not store it at home.

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Edited Arsenic Trioxide Overview: 14 years ago

Created: 2006-10-13 10:45:10.0

Modified: 2010-03-26 12:43:08.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• This medicine is used to treat specific types of leukemias and bone marrow disorders.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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What are the precautions when taking this medicine?

• If you have kidney disease, talk with healthcare provider.

• If you have a weakened heart, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Use birth control that you can trust to prevent pregnancy while taking this medicine.

What are some possible side effects of this medicine?

• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Cough.

• Headache.

• Swelling.

• Belly pain.

• Diarrhea.

• Constipation.

• High blood sugar.

• Feeling tired or weak.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.

• Difficulty breathing.

• Fast heartbeat.

• Severe dizziness or passing out.

• Significant change in thinking clearly and logically.

• Increased trips to the bathroom, increased thirst, or weight loss.

• Severe diarrhea.

• Unusual bruising or bleeding.

• Any rash.

• No improvement in condition or feeling worse.

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