• Dangerous allergic reactions can occur. Tell healthcare provider about any fever, rash, feeling tired, nausea, vomiting, diarrhea, belly pain, flu-like symptoms, sore throat, cough, or difficulty breathing. Do not restart this medicine if you have had an allergic reaction.
• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.
• If you have an allergy to asparaginase or any other part of this medicine.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
• If this medicine caused bleeding, a blood clot, or an irritated pancreas before.
• If you are pregnant or may be pregnant.
• If you are breast-feeding.
• This medicine is given as a shot into a muscle, vein, or into the fatty part of the skin.
• Change in condition being treated. Is it better, worse, or about the same?
• Check blood work regularly. Talk with healthcare provider.
• Take good care of your teeth. See a dentist regularly.
• Follow up with healthcare provider.
• This medicine will be given to you in a healthcare setting. You will not store it at home.
Created: 2005-04-07 16:19:30.0
Modified: 2010-03-09 08:27:57.0
Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.
• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.
• If you have any circulation problems, talk with healthcare provider.
• If you have diabetes, talk with healthcare provider.
• If you have pancreatic disease, talk with healthcare provider.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• You may bleed more easily. Be careful. Avoid injury. Use soft toothbrush, electric razor.
• Tell dentists, surgeons, and other healthcare providers that you use this medicine.
• Use birth control that you can trust to prevent pregnancy while taking this medicine.
• If you are a male and sexually active, protect your partner from pregnancy. Use birth control that you can trust.
• Fever and chills while medicine is being given. Medicines may be given to prevent this.
• Bleeding problems.
• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• High blood sugar. Usually reverses when stopped.
• Seizures can rarely occur.
• Severe allergic reactions can rarely occur.
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.
• Signs or symptoms of depression, suicidal thoughts, nervousness, emotional ups and downs, abnormal thinking, anxiety, or lack of interest in life.
• Significant change in thinking clearly and logically.
• Severe nausea or vomiting.
• Severe belly pain.
• Not able to eat.
• Unusual bruising or bleeding.
• Dark urine or yellow skin or eyes.
• Feeling extremely tired or weak.
• Increased trips to the bathroom, increased thirst, or weight loss.
• Any rash.
• No improvement in condition or feeling worse.
