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Bevacizumab Contributions by FoundHealth

Article Revisions

Edited Bevacizumab Overview: Overview 14 years ago

(be vuh SIZ uh mab)

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Avastin®

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Avastin®

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Avastin

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Antineoplastic Agent, Monoclonal Antibody; Vascular Endothelial Growth Factor (VEGF) Inhibitor

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• Serious holes in the gastrointestinal tract, incomplete wound healing, fistulas, and severe bleeding have been reported. Talk with healthcare provider.

• This medicine does not mix well with some medicines. Serious reactions may occur. Check all medicines with healthcare provider.

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• If you have an allergy to bevacizumab or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you are pregnant or may be pregnant.

• If you are breast-feeding.

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• Bevacizumab injures cancer cells causing their death.

• It slows vision loss.

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• This medicine is given as a shot into the eye.

• This medicine is given as a shot into a vein over a period of time.

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• Call healthcare provider for appointment.

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• Change in condition being treated. Is it better, worse, or about the same?

• Bowel movements.

• Check blood pressure regularly. Talk with healthcare provider.

• Check blood work regularly. Talk with healthcare provider.

• Check urine regularly. Talk with healthcare provider.

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• This medicine will be given to you in a healthcare setting. You will not store it at home.

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Edited Bevacizumab Overview: 14 years ago

Created: 2006-10-13 10:57:20.0

Modified: 2010-06-22 09:56:46.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• This medicine is used to treat a variety of cancers.

• This medicine is used to treat macular degeneration.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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What are the precautions when taking this medicine?

Injection:

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• If you have heart disease, talk with healthcare provider.

• If you have had blood clots, talk with healthcare provider.

• If you have high blood pressure, talk with healthcare provider.

• Tell dentists, surgeons, and other healthcare providers that you use this medicine.

• You may bleed more easily. Be careful. Avoid injury. Use soft toothbrush, electric razor.

• Talk with healthcare provider before using other: aspirin, aspirin-containing products, blood thinners, garlic, ginseng, ginkgo, ibuprofen or like products, pain medicines, or vitamin E.

• Use birth control that you can trust to prevent pregnancy.

Eye:

• If you have glaucoma, talk with healthcare provider.

What are some possible side effects of this medicine?

Injection:

• Bleeding problems.

• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.

• Headache.

• Belly pain.

• Back pain.

• High or low blood pressure.

• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Diarrhea.

• Feeling tired or weak.

• Not hungry.

• Delayed wound healing.

• Skin irritation.

Eye:

• Increased eye pressure.

• Eye infection.

• Eye irritation.

• Blurred vision. Use caution when driving or doing other tasks that require you to have clear vision.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Severe dizziness or passing out.

• Difficulty breathing.

• Swelling of legs or belly.

• Severe headache.

• Seizures.

• Significant change in thinking clearly and logically.

• Sudden change in vision, eye pain, or irritation.

• Severe nausea or vomiting.

• Severe constipation.

• Severe belly pain.

• Severe diarrhea.

• Numbness or tingling of hands or feet.

• Skin wound that will not heal.

• Cloudy or pink-red urine.

• Unusual bruising or bleeding.

• Any rash.

• No improvement in condition or feeling worse.

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