Bupropion may be associated with a higher incidence of drug-induced seizures. In addition to seizures, bupropion may cause the following side effects:
• You may have certain heart tests before starting this medicine. Talk with healthcare provider.
• If you are 65 or older, use this medicine with caution. You could have more side effects.
• If you are allergic to tartrazine, talk with healthcare provider. Some products contain tartrazine.
• Do not use Zyban® and Wellbutrin® together. They are the same medicine.
• If you have been taking this medicine for several weeks, talk with healthcare provider before stopping. You may want to gradually withdraw this medicine.
• If you abuse alcohol or cocaine, talk with healthcare provider.
• If you have heart disease, talk with healthcare provider.
• If you have kidney disease, talk with healthcare provider.
• If you have liver disease, talk with healthcare provider.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.
• Avoid alcohol (includes wine, beer, and liquor) or other medicines and natural products that slow your actions and reactions.
• Tell healthcare provider if you are pregnant or plan on getting pregnant.
• Tell healthcare provider if you are breast-feeding.
• Feeling lightheaded, sleepy, having blurred vision, or a change in thinking clearly. Avoid driving, doing other tasks or activities that require you to be alert or have clear vision until you see how this medicine affects you.
• Long-acting tablet shell in the stool.
• Hot flashes. Wearing layers of clothes or summer clothes and cool environment may help.
• Headache.
• Belly pain.
• Shakiness.
• Nervous and excitable.
• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.
• Dry mouth. Frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• Inability to sleep.
• Abnormal taste. This is usually reversible.
• Not hungry.
• Severe allergic reactions can rarely occur.
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Signs or symptoms of depression, suicidal thoughts, nervousness, emotional ups and downs, abnormal thinking, anxiety, or lack of interest in life.
• Significant change in thinking clearly and logically.
• Fast heartbeat.
• Severe headache.
• Very nervous and excitable.
• If seizures are new or worse after starting medicine.
• Any rash.
• No improvement in condition or feeling worse.
Bupropion is an atypical antidepressant that inhibits the reuptake of norepinephine in the brain. It is commonly used as a smoking cessation aid and is sometimes used in the treatment of attention deficit hyperactivity disorder.
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Aplenzin™; Budeprion SR®; Budeprion XL®; Buproban®; Wellbutrin SR®; Wellbutrin XL®; Wellbutrin®; Zyban®
Bupropion SR®; Novo-Bupropion SR; PMS-Bupropion SR; ratio-Bupropion SR; Sandoz-Bupropion SR; Wellbutrin® SR; Wellbutrin® XL; Zyban®
• The desire to harm yourself is a serious symptom of depression. It may last until your depression is completely treated. If you are planning on harming yourself, call the emergency department right away.
• When used for smoking cessation may cause or worsen diseases of the mind. Suicide, ideas of suicide or homicide, depression, aggressive behavior, hallucinations, and psychoses have occurred with use. If you suspect any of these problems, call healthcare provider right away.
• Both Wellbutrin® and Zyban® contain the same active ingredient. You should not take both medicines at the same time.
• Risk of seizures may be increased. Talk with healthcare provider.
• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.
• Please read the medication guide.
• If you have an allergy to bupropion or any other part of this medicine.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
• If you have any of the following conditions: Eating disorder or seizures.
• If you have taken isocarboxazid, phenelzine, or tranylcypromine in the last 14 days. Monoamine oxidase inhibitors (eg, isocarboxazid, phenelzine, and tranylcypromine) must be stopped 14 days before this medicine is started. Taking the two together could cause dangerously high blood pressure.
• Bupropion increases chemicals in the brain.
• In depression, sleep and appetite may improve quickly. Other depressive symptoms may take up to 4-6 weeks to improve.
• It relieves the craving and withdrawal symptoms from smoking.
• It has a stabilizing effect in attention deficit disorder.
• Take a missed dose as soon as possible.
• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
• Do not take a double dose or extra doses.
• Do not change dose or stop medicine. Talk with healthcare provider.
• Store at room temperature.
• Protect from light.
• Protect from moisture. Do not store in a bathroom or kitchen.
Created: 2006-10-13 11:04:52.0
Modified: 2010-03-24 11:35:57.0
Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.
• To gain the most benefit, do not miss doses.
• Take this medicine with or without food. Take with food if it causes an upset stomach.
• Long-acting products: Swallow whole. Do not chew, break, or crush.
• You may take this medicine for 1 week before you stop smoking.
• Nicotine replacement and counseling may be used at the same time for best results.
• Swallow Wellbutrin® SR whole or as a half. Do not crush or chew.
• Change in condition being treated. Is it better, worse, or about the same?
• Check blood pressure regularly if you have heart disease or are taking a nicotine replacement product.
• Dry mouth may cause an increase in cavities. Take good care of your teeth. See a dentist regularly.
• Follow up with healthcare provider.
• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
• This medicine is used to help you stop smoking.
• This medicine is used to treat depression.
• This medicine is used to treat attention deficit disorder with hyperactivity.
