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Chlorambucil Contributions by FoundHealth

Article Revisions

Edited Chlorambucil Overview: Overview 14 years ago

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Leukeran®

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Leukeran®

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Leukeran

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Antineoplastic Agent, Alkylating Agent

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• This medicine is very strong. It can prevent your bone marrow from making some of the cells that your body needs. You will be closely monitored by healthcare provider. Tell healthcare provider right away about any fever, sore throat, signs of infection, bleeding, shortness of breath, or feeling tired.

• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.

• This medicine may cause infertility. Talk with healthcare provider.

• Other forms of cancer can rarely occur later in life.

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• If you have an allergy to chlorambucil or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you are pregnant or may be pregnant.

• If you are breast-feeding.

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• Chlorambucil injures cancer cells causing their death.

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• Take this medicine at a similar time of day.

• Take this medicine with food.

• A liquid (suspension) is available if you cannot swallow pills. Shake well before use.

• Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after medicine is given.

• Drink plenty of noncaffeine-containing liquid unless told to drink less liquid by healthcare provider.

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• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

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• Change in condition being treated. Is it better, worse, or about the same?

• Check blood work regularly. Talk with healthcare provider.

• Follow up with healthcare provider.

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• Store in a refrigerator. Do not freeze.

• Protect from light.

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Edited Chlorambucil Overview: 14 years ago

Created: 2006-10-13 11:21:34.0

Modified: 2010-03-23 11:05:47.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• This medicine is used to treat a variety of cancers.

• This medicine is used to treat leukemia.

• This medicine is used to treat lymphoma.

• This medicine is used to treat blood disorders.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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What are the precautions when taking this medicine?

• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.

• If you have seizures or are on seizure medicine, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• You may bleed more easily. Be careful. Avoid injury. Use soft toothbrush, electric razor.

• Talk with healthcare provider before using other: aspirin, aspirin-containing products, blood thinners, garlic, ginseng, ginkgo, ibuprofen or like products, pain medicines, or vitamin E.

• Use birth control that you can trust to prevent pregnancy while taking this medicine.

• If you are a male and sexually active, protect your partner from pregnancy. Use birth control that you can trust.

What are some possible side effects of this medicine?

• Infertility.

• Risk of infection. Avoid people with infections, colds, or flu.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Mouth irritation. Frequent mouth care with a soft toothbrush or cotton swabs and rinsing mouth may help.

• Anemia, low white blood cell count, and low platelet count.

• Other forms of cancer can rarely occur later in life.

• Seizures can rarely occur.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.

• Significant change in thinking clearly and logically.

• Difficulty breathing.

• Persistent cough.

• Severe belly pain.

• Severe nausea or vomiting.

• Severe diarrhea.

• Unusual bruising or bleeding.

• Dark urine or yellow skin or eyes.

• Any rash.

• No improvement in condition or feeling worse.

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