• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.
• If you have an allergy to cyclophosphamide or any other part of this medicine.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
• If you are pregnant or may be pregnant.
• If you are breast-feeding.
• Cyclophosphamide injures cancer cells causing their death.
• It decreases the body's harmful response to diseases affecting the immune system.
• Take this medicine with food to prevent stomach upset.
• Drink plenty of noncaffeine-containing liquid unless told to drink less liquid by healthcare provider.
• The injection is given as a shot into a vein.
• Take a missed dose as soon as possible.
• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
• Do not take a double dose or extra doses.
• Do not change dose or stop medicine. Talk with healthcare provider.
• Change in condition being treated. Is it better, worse, or about the same?
• Check blood work regularly. Talk with healthcare provider.
• Follow up with healthcare provider.
• Store at room temperature.
• Protect from moisture. Do not store in a bathroom or kitchen.
Created: 2005-04-07 16:31:01.0
Modified: 2010-03-09 08:28:11.0
Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.
• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
• This medicine is used as therapy in preparation for bone marrow transplantation.
• This medicine is used to treat rheumatoid arthritis.
• This medicine is used to treat Wegener's granulomatosis.
• This medicine is used to treat antibody-induced pure red cell aplasia.
• This medicine is used to treat autoimmune hemolytic anemia.
• This medicine is used to treat a variety of cancers.
• This medicine is used to treat idiopathic thrombocytic purpura (ITP).
• This medicine is used to treat lupus.
• This medicine is used to treat macroglobulinemia.
• This medicine is used to treat multiple sclerosis.
• This medicine is used to treat myasthenia gravis.
• If you are 65 or older, use this medicine with caution. You could have more side effects.
• If you have kidney disease, talk with healthcare provider.
• If you have liver disease, talk with healthcare provider.
• If you have a weakened heart, talk with healthcare provider.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.
• Talk with healthcare provider before using aspirin, aspirin-containing products, other pain medicines, blood thinners, garlic, ginseng, ginkgo, or vitamin E.
• Urinate often. It is important to empty your bladder often. Drinking plenty of liquids will help.
• Use birth control that you can trust to prevent pregnancy while taking this medicine.
• If you are a male and sexually active, protect your partner from pregnancy. Use birth control that you can trust.
• Risk of infection. Avoid people with infections, colds, or flu.
• Headache.
• Anemia, low white blood cell count, and low platelet count.
• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• Hair loss. Hair usually grows back when medicine is stopped.
• Infertility.
• Other forms of cancer can rarely occur later in life.
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.
• Shortness of breath.
• Severe belly pain.
• Severe nausea or vomiting.
• Severe back pain.
• Not able to eat.
• Unusual bruising or bleeding.
• Dark urine or yellow skin or eyes.
• Blood in the urine.
• Unable to pass urine.
• Feeling extremely tired or weak.
• Any rash.
• No improvement in condition or feeling worse.
