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Dacarbazine Contributions by FoundHealth

Article Revisions

Edited Dacarbazine Overview: Overview 14 years ago

(da KAR ba zeen)

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DTIC®

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Detilem

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Antineoplastic Agent, Alkylating Agent (Triazene)

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• This medicine is very strong. It can cause liver damage. It can prevent your bone marrow from making some of the cells that your body needs. You will need weekly blood work to watch for side effects. Tell healthcare provider right away about any fever, sore throat, signs of infection, bleeding, shortness of breath, or feeling tired.

• This medicine can cause cancer in animals. Talk with healthcare provider.

• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.

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• If you have an allergy to dacarbazine or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you are pregnant or may be pregnant.

• If you are breast-feeding.

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• Dacarbazine injures cancer cells causing their death.

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• This medicine is given into a vein constantly for a period of time.

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• Call healthcare provider for appointment.

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• Change in condition being treated. Is it better, worse, or about the same?

• Check blood work regularly. Talk with healthcare provider.

• Take good care of your teeth. See a dentist regularly.

• Follow up with healthcare provider.

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• This medicine will be given to you in a healthcare setting. You will not store it at home.

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Edited Dacarbazine Overview: 14 years ago

Created: 2006-10-13 11:44:34.0

Modified: 2010-04-27 14:32:14.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• This medicine is used to treat a variety of cancers.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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What are the precautions when taking this medicine?

• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.

• If you have kidney disease, talk with healthcare provider.

• If you have liver disease, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• You may bleed more easily. Be careful. Avoid injury. Use soft toothbrush, electric razor.

• Talk with healthcare provider before using other: aspirin, aspirin-containing products, blood thinners, garlic, ginseng, ginkgo, ibuprofen or like products, pain medicines, or vitamin E.

• Tell dentists, surgeons, and other healthcare providers that you use this medicine.

• You can get sunburned more easily. Avoid sun, sunlamps, bright indoor lights, and tanning beds. Wear protective clothing and eyewear. Sunscreens will not protect you.

• Use birth control that you can trust to prevent pregnancy while taking this medicine.

What are some possible side effects of this medicine?

• Risk of infection. Avoid people with infections, colds, or flu.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Diarrhea.

• Hair loss. Hair usually grows back when medicine is stopped.

• Sunburn.

• Low white blood cell count or low platelet count.

• Irritation where the shot is given.

• Irritation or swelling at the injection site.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.

• Severe dizziness or passing out.

• Severe nausea or vomiting.

• Severe diarrhea.

• Unusual bruising or bleeding.

• Dark urine or yellow skin or eyes.

• Feeling extremely tired or weak.

• Not able to eat.

• Any rash.

• No improvement in condition or feeling worse.

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