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Decitabine Contributions by FoundHealth

Article Revisions

Edited Decitabine Overview: Overview 14 years ago

(de SYE ta been)

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Dacogen®

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Antineoplastic Agent, DNA Methylation Inhibitor

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• If you have an allergy to decitabine or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you are pregnant or may be pregnant.

• If you are breast-feeding.

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• Decitabine injures cancer cells causing their death.

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• This medicine is given as a shot into a vein over a period of time.

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• Call healthcare provider for appointment.

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• Change in condition being treated. Is it better, worse, or about the same?

• Check blood work (blood counts, liver and kidney function) regularly. Talk with healthcare provider.

• Follow up with healthcare provider.

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• This medicine will be given to you in a healthcare setting. You will not store it at home.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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Edited Decitabine Overview: 14 years ago

Created: 2006-10-13 11:48:42.0

Modified: 2010-04-21 08:15:36.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• This medicine is used to treat specific types of leukemias and bone marrow disorders.

• This medicine is used to treat sickle cell anemia.

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What are the precautions when taking this medicine?

• If you have kidney disease, talk with healthcare provider.

• If you have liver disease, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Use two forms of birth control that you can trust 1 month before treatment begins, during treatment, and for at least 1 month after treatment ends.

• If you are a male and sexually active, protect your partner from pregnancy. Use two forms of birth control that you can trust 1 month before treatment begins, during treatment, and for at least 2 months after treatment ends.

What are some possible side effects of this medicine?

• Anemia, low white blood cell count, and low platelet count.

• Risk of infection. Avoid people with infections, colds, or flu.

• Fever.

• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.

• Feeling tired or weak.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Mouth irritation. Frequent mouth care with a soft toothbrush or cotton swabs and rinsing mouth may help.

• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.

• Diarrhea.

• High blood sugar.

• Cough.

• Inability to sleep.

• Swelling.

• Not hungry.

• Headache.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.

• Difficulty breathing.

• Severe dizziness or passing out.

• Severe nausea or vomiting.

• Severe constipation.

• Severe diarrhea.

• Unusual bruising or bleeding.

• Any rash.

• No improvement in condition or feeling worse.

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