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Denileukin Diftitox Contributions by FoundHealth

Article Revisions

(de ni LOO kin DIF ti toks)

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ONTAK®

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Antineoplastic Agent, Miscellaneous

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• Some patients experience severe reactions during the infusion. A sudden change in vision or in the way you see color may occur. Rapid weight gain, swelling, and low blood pressure may occur.

• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.

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• If you have an allergy to denileukin diftitox or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you are pregnant or may be pregnant.

• If you are breast-feeding.

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• Denileukin diftitox injures cancer cells causing their death.

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• This medicine is given as a shot into a vein.

• Drink plenty of noncaffeine-containing liquid unless told to drink less liquid by healthcare provider.

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• Call healthcare provider for appointment.

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• Change in condition being treated. Is it better, worse, or about the same?

• Check blood work regularly. Talk with healthcare provider.

• Check blood pressure and heart rate regularly. Talk with healthcare provider.

• Check weight weekly. Report a weight change to healthcare provider.

• Follow up with healthcare provider.

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• This medicine will be given to you in a healthcare setting. You will not store it at home.

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Edited Denileukin Diftitox Overview: 14 years ago

Created: 2006-10-13 11:50:14.0

Modified: 2010-03-25 11:43:14.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• This medicine is used to treat lymphoma.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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What are the precautions when taking this medicine?

• If you are 65 or older, use this medicine with caution. You could have more side effects.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.

• Use birth control that you can trust to prevent pregnancy while taking this medicine.

What are some possible side effects of this medicine?

• Risk of infection. Avoid people with infections, colds, or flu.

• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.

• Flu-like symptoms. These include headache, weakness, fever, shakes, aches, pains, and sweating. Mild pain medicine may help.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Not hungry.

• Diarrhea.

• Itching.

• Rash.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.

• Difficulty breathing.

• Chest pain or pressure, fast heartbeat, or passing out.

• Significant change in thinking clearly and logically.

• Significant weight loss.

• Significant weight gain.

• Severe nausea or vomiting.

• Severe diarrhea.

• Unusual bruising or bleeding.

• Dark urine or yellow skin or eyes.

• Feeling extremely tired or weak.

• Severe swelling.

• Sudden change in vision or in the way you see color.

• Any rash.

• No improvement in condition or feeling worse.

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