• This medicine does not mix well with some medicines. Serious reactions may occur. Check all medicines with healthcare provider.
• If you have an allergy to dexrazoxane or any other part of this medicine.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
• If you are breast-feeding.
• Dexrazoxane protects the heart from doxorubicin.
• Dexrazoxane protects the skin from certain medicines.
• This medicine is given as a shot into a vein.
• This medicine is given with your cancer medicine.
• This medicine must be taken exactly as directed.
• If you are using ice on the damaged skin, remove the ice 15 minutes before your shot.
• Change in condition being treated. Is it better, worse, or about the same?
• Check blood work regularly. Talk with healthcare provider.
• Heart function tests. Talk with healthcare provider.
• Follow up with healthcare provider.
• This medicine will be given to you in a healthcare setting. You will not store it at home.
• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
Created: 2005-04-07 16:33:03.0
Modified: 2010-03-09 08:22:28.0
Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.
• This medicine is used to decrease the side effects of doxorubicin.
• This medicine is used to prevent skin damage from certain medicines.
• If you have kidney disease, talk with healthcare provider.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• Tell healthcare provider if you are pregnant or plan on getting pregnant.
• Risk of infection. Avoid people with infections, colds, or flu.
• Flu-like symptoms. These include headache, weakness, fever, shakes, aches, pains, and sweating. Mild pain medicine may help.
• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• Anemia, low white blood cell count, and low platelet count.
• Irritation where the shot is given.
• Diarrhea.
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.
• Unusual bruising or bleeding.
• Feeling extremely tired or weak.
• Any rash.
• No improvement in condition or feeling worse.