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Diphenoxylate and Atropine Contributions by FoundHealth

Article Revisions

(dye fen OKS i late & A troe peen)

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Lomotil®; Lonox®

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Lomotil®

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Antidiarrheal

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• Do not give this medicine to a child younger than 2 years of age.

• If you have an allergy to diphenoxylate, atropine, or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you have any of the following conditions: Diarrhea caused by infection, liver disease, or yellowing of the skin or eyes.

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• Diphenoxylate slows movement through the gastrointestinal tract allowing more water to be reabsorbed.

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• Take this medicine with or without food. Take with food if it causes an upset stomach.

• Follow directions given by healthcare provider. Do not use more than the maximum recommended daily dose.

• A liquid (solution) is available if you cannot swallow pills.

• Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after medicine is given.

• Use the dropper provided to measure the medicine.

• Drink plenty of noncaffeine-containing liquid unless told to drink less liquid by healthcare provider.

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• This medicine is taken on an as needed basis.

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• Change in condition being treated. Is it better, worse, or about the same?

• Dry mouth may cause an increase in cavities. Take good care of your teeth. See a dentist regularly.

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• Store at room temperature.

• Protect from light.

• Protect tablets from moisture. Do not store in a bathroom or kitchen.

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Created: 2006-10-13 12:02:25.0

Modified: 2010-03-19 13:46:20.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• Diphenoxylate is used to treat diarrhea.

• Atropine prevents abuse of this medicine.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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What are the precautions when taking this medicine?

• This medicine may be habit-forming with long-term use.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.

• Avoid alcohol (includes wine, beer, and liquor) or other medicines and natural products that slow your actions and reactions.

• Tell healthcare provider if you are breast-feeding.

• Tell healthcare provider if you are pregnant or plan on getting pregnant.

What are some possible side effects of this medicine?

• Dry mouth. Frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Feeling lightheaded, sleepy, having blurred vision, or a change in thinking clearly. Avoid driving, doing other tasks or activities that require you to be alert or have clear vision until you see how this medicine affects you.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Any rash.

• No improvement in condition or feeling worse.

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