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Divalproex Contributions by FoundHealth

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• Change in condition being treated. Is it better, worse, or about the same?

• Check blood work (liver function). Talk with healthcare provider.

• Follow up with healthcare provider.

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• Store at room temperature.

• Protect from moisture. Do not store in a bathroom or kitchen.

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Edited Divalproex Overview: 14 years ago

Created: 2009-12-27 11:55:01.0

Modified: 2010-04-07 10:10:41.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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What are the precautions when taking this medicine?

• Wear disease medical alert identification.

• Follow laws about driving with a seizure condition.

• If you have been taking this medicine for several weeks, talk with healthcare provider before stopping. You may want to gradually withdraw this medicine.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.

• Avoid alcohol (includes wine, beer, and liquor) or other medicines and natural products that slow your actions and reactions.

• Use birth control that you can trust to prevent pregnancy while taking this medicine.

What are some possible side effects of this medicine?

• Feeling lightheaded, sleepy, having blurred vision, or a change in thinking clearly. Avoid driving, doing other tasks or activities that require you to be alert or have clear vision until you see how this medicine affects you.

• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.

• Headache.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Diarrhea.

• Belly pain.

• Hair loss.

• Muscle weakness.

• Inability to sleep.

• Depakote® Sprinkle bits in stool.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of depression, suicidal thoughts, nervousness, emotional ups and downs, abnormal thinking, anxiety, or lack of interest in life.

• Severe nausea or vomiting.

• Severe belly pain.

• Not able to eat.

• Significant change in balance.

• Unusual bruising or bleeding.

• Dark urine or yellow skin or eyes.

• Feeling extremely tired or weak.

• If seizures are worse or different after starting medicine.

• For females, if you are pregnant or may be pregnant.

• Any rash.

• No improvement in condition or feeling worse.

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Edited Divalproex Overview: Overview 14 years ago

(dye VAL proe ex)

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Depakote®; Depakote® ER; Depakote® Sprinkle

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Apo-Divalproex®; Dom-Divalproex; Epival®; Mylan-Divalproex; Novo-Divalproex; Nu-Divalproex; PHL-Divalproex; PMS-Divalproex

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Anticonvulsant, Miscellaneous; Antimanic Agent; Histone Deacetylase Inhibitor

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• This medicine may cause liver problems. Call healthcare provider if you notice dark urine, feeling tired, not hungry, nausea, vomiting, or yellowing of the skin or eyes. Do not take this medicine if you are pregnant. This medicine may irritate the pancreas (pancreatitis). This could occur in children or adults at any time during treatment. Signs of pancreatitis include belly pain, nausea, vomiting, or decreased appetite. Contact healthcare provider right away if you have any of these symptoms.

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• If you have an allergy to valproic acid or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you have liver disease.

• If you are pregnant or may be pregnant.

• If you are breast-feeding.

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• Divalproex helps clear thinking.

• It increases the amount of a chemical called gamma-aminobutyric in the brain. This chemical decreases excitability of the brain.

• It is a mood stabilizer.

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• Take this medicine with or without food. Take with food if it causes an upset stomach.

• Swallow whole. Do not chew, break, or crush.

• You may sprinkle contents of Depakote® Sprinkle® capsule on soft food or liquid. Do not chew.

• Take this medicine with a full glass of water.

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• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

• Do not change dose or stop medicine. This could cause seizures. Talk with healthcare provider.

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• This medicine is used to prevent migraine headaches.

• This medicine is used to prevent or control seizures.

• This medicine is used to treat behavior problems.

• This medicine is used to treat manic depression.

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