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Eculizumab Contributions by FoundHealth

Article Revisions

Edited Eculizumab Overview: Overview 14 years ago

(e kue LIZ oo mab)

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Soliris®

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Monoclonal Antibody; Monoclonal Antibody, Complement Inhibitor

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• Serious meningococcal infections have occurred in patients who have taken this medication. You should receive a meningococcal vaccine at least 2 weeks before starting this medicine.

• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.

• Please read the medication guide.

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• If you have an allergy to eculizumab or any other part of this medicine.

• If you have not received a meningococcal vaccine.

• If you have a meningococcal infection.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

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• Eculizumab prevents the break down of red blood cells.

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• Use prescription as directed, even if feeling better.

• This medicine is given as a shot into a vein.

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• Call healthcare provider for instructions.

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• Change in condition being treated. Is it better, worse, or about the same?

• Check blood work regularly. Talk with healthcare provider.

• Follow up with healthcare provider.

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• This medicine will be given to you in a healthcare setting. You will not store it at home.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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Edited Eculizumab Overview: 14 years ago

Created: 2007-03-22 11:05:17.0

Modified: 2010-03-09 08:26:05.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• This medicine is used to treat a blood disease called paroxysmal nocturnal hemoglobinuria (PNH).

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What are the precautions when taking this medicine?

• Serious infections have been reported with use of this medicine. If you have any infection, are taking antibiotics now or in the recent past, or have many infections, talk with healthcare provider.

• Make sure you are current with all your vaccinations.

• Have patient safety card with you at all times.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.

• Tell healthcare provider if you are pregnant or plan on getting pregnant.

• Tell healthcare provider if you are breast-feeding.

What are some possible side effects of this medicine?

• Flu-like symptoms. These include headache, weakness, fever, shakes, aches, pains, and sweating. Mild pain medicine may help.

• Risk of infection. Avoid people with infections, colds, or flu.

• Headache.

• Sore throat.

• Back pain.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Feeling tired or weak.

• Cough.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.

• Significant change in thinking clearly and logically.

• Severe headache.

• Neck stiffness.

• Severe nausea or vomiting.

• Severe muscle pain.

• Cloudy or pink-red urine.

• Dark urine.

• Any rash.

• No improvement in condition or feeling worse.

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