• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.
• If you have an allergy to ergotamine, caffeine, or any other part of this medicine.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
• If you have any of the following conditions: Blood clots, heart disease, high blood pressure, kidney disease, liver disease, poor blood flow to the legs, Raynaud's disease, severe infection, or thromboangiitis obliterans.
• If you have taken almotriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, or zolmitriptan in the last 24 hours.
• If you are pregnant or may be pregnant.
• If you are breast-feeding.
• Ergotamine squeezes certain blood vessels in the brain preventing irritation and inflammation.
• Caffeine relieves pain.
Oral:
• Take two tablets at the first sign of attack.
• Take one tablet 30 minutes after the first dose, if needed. Separate doses by at least 30 minutes.
• Do not take more than 6 tablets per attack or more than 10 tablets a week.
Rectal:
• Use suppository rectally.
• Do not use more than 2 suppositories per attack or more than 5 suppositories a week.
• Change in condition being treated. Is it better, worse, or about the same?
• Follow up with healthcare provider.
• Store at room temperature.
• Protect from moisture. Do not store in a bathroom or kitchen.
Created: 2005-04-07 16:38:19.0
Modified: 2010-03-09 08:24:10.0
Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.
• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
• This medicine may be habit-forming with long-term use.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• Avoid grapefruit and grapefruit juice.
• Avoid caffeine (for example, tea, coffee, cola) and chocolate intake.
• Use birth control that you can trust to prevent pregnancy while taking this medicine.
• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.
• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Chest pain or pressure or fast heartbeat.
• Numbness or tingling of hands or feet.
• Severe dizziness or passing out.
• Difficulty breathing.
• Severe headache.
• Severe nausea or vomiting.
• Weakness.
• Any rash.
• No improvement in condition or feeling worse.
