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Esomeprazole Contributions by FoundHealth

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Side effects

Below are the most common side effects that may occur with Esomprazole use. Contact your doctor if these symptoms persist or become bothersome:

  • headache
  • nausea
  • diarrhea
  • dry mouth
  • flatulence
  • abdominal pain
  • constipation

Seek medical attention immediately if any of these side effects occur when using Esomeprazole:

  • signs and symptoms of allergic reactions such as rash, itching; difficulty breathing, tightness in the chest, swelling of the face, lips, or tongue, or unusual hoarseness
  • chest pain
  • dark urine
  • fast heartbeat
  • fever or chills
  • persistent sore throat
  • skin changes: redness, swelling, peeling, blisters severe abdominal pain unusual bruising or bleeding unusual tiredness jaundice or yellowish discoloration of the skin

Contraindications

Esomeprazole is contraindicated in patients with known hyper-sensitivity to any of its components or to substituted benzimidazoles.

Drug interactions

Clinical studies have shown that some drugs may interact with Esomeprazole. Tell your doctor if you are using any of the following:

  • clopidogrel (Plavix);
  • digoxin (Lanoxin, Lanoxicaps);
  • diazepam (Valium);
  • ketoconazole (Nizoral);
  • HIV or AIDS medication such as atazanavir (Reyataz), nelfinavir (Viracept), saquinavir (Invirase), and others;
  • Iron (Feosol, Mol-Iron, Fergon, Femiron, others); or
  • warfarin (Coumadin).
  • Phenytoin

Tell your doctor about all the prescription and non prescription drugs you use. This includes supplements, vitamins, minerals, herbal products, as well as drugs prescribed by other doctors.

Before taking Esomeprazole, it is important to tell your doctor if you've had liver problems or any type of heart disease. Some cases may require dose adjustment or special tests while on Esomeprazole therapy

What are the precautions when taking this medicine?

• If you have liver disease, talk with healthcare provider.

• Use caution if you have risk factors for osteoporosis (alcohol use, cigarette smoking, other family members with osteoporosis, taking medicines to treat seizures, taking steroids).

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Avoid alcohol (includes wine, beer, and liquor).

• Tell healthcare provider if you are pregnant or plan on getting pregnant.

• Tell healthcare provider if you are breast-feeding.

What are some possible side effects of this medicine?

• Headache.

• Diarrhea.

• Hip, spine, or wrist fractures may rarely occur.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Severe dizziness or passing out.

• Severe diarrhea.

• Severe belly pain.

• Severe bone pain.

• Unusual bruising or bleeding.

• Any rash.

• No improvement in condition or feeling worse.

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Edited Esomeprazole Overview: Overview 14 years ago

Esomeprazole is prescribed to treat the symptoms of acid reflux disease and to heal acid-related damage to the esophagus. It is also used with other drugs to prevent stomach ulcers. Like other proton pump inhibitors, Esomeprazole works by stopping many of the "acid pumps" in the cells of the stomach. As a result, the stomach content becomes less acidic. Esomeprazole can both relieve heartburn pain and heal possible damage on the lining of the esophagus.

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Nexium®

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Nexium®

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Nexium IV; Nexium-MUPS

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Proton Pump Inhibitor; Substituted Benzimidazole

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• This medicine does not mix well with some medicines. Serious reactions may occur. Check all medicines with healthcare provider.

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• If you have an allergy to esomeprazole or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

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• Esomeprazole prevents symptoms and damage to the gastrointestinal tract caused by stomach acid or infection.

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• Take this medicine at a similar time of day.

• Take this medicine 1 hour before the first meal of the day.

Capsule:

• Swallow capsule whole. Do not chew, break, or crush.

• You may sprinkle contents of capsule on soft food or liquid. Do not chew.

• Those who have feeding tubes can make a liquid. Empty contents of capsule into a syringe with 2 ounces of water. Replace plunger and shake for 15 seconds. Flush feeding tube before and after medicine is taken.

Granules:

• Mix granules with tablespoon of water; let sit for a few minutes. Mix and drink.

• Rinse with more water and drink.

Injection (I.V.):

• This medicine is given as a shot into a vein.

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• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

• Do not change dose or stop medicine. Talk with healthcare provider.

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• Change in condition being treated. Is it better, worse, or about the same?

• Follow up with healthcare provider.

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• Store capsules and granules at room temperature.

• Protect capsules and granules from moisture. Do not store in a bathroom or kitchen.

• The injection will be given to you in a healthcare setting. You will not store it at home.

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Edited Esomeprazole Overview: 14 years ago

Created: 2006-10-13 12:20:50.0

Modified: 2010-06-01 11:56:59.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• This medicine is used to prevent or treat gastrointestinal ulcers caused by infection.

• This medicine is used to prevent or treat ulcers of the esophagus (swallowing tube).

• This medicine is used to treat syndromes caused by huge amounts of stomach acid.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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