Antineoplastic Agent, Alkylating Agent; Antineoplastic Agent, Hormone; Antineoplastic Agent, Hormone (Estrogen/Nitrogen Mustard)
• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.
• If you have an allergy to estramustine or any other part of this medicine.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
• If you have blood clots.
• Estramustine injures cancer cells causing their death.
• Estramustine slows prostate cancer growth by lowering testosterone levels.
• Take this medicine on an empty stomach. Take 1 hour before or 2 hours after meals.
• Take this medicine with a full glass of water.
• Do not take dairy products or calcium within 2 hours of this medicine.
• Take a missed dose as soon as possible.
• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
• Do not take a double dose or extra doses.
• Change in condition being treated. Is it better, worse, or about the same?
• Check blood work regularly. Talk with healthcare provider.
• If you are diabetic, you will need to monitor blood sugars closely.
• Check blood pressure regularly. Talk with healthcare provider.
Created: 2006-10-13 12:22:10.0
Modified: 2010-04-06 12:40:54.0
Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.
• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• If you have diabetes, talk with healthcare provider.
• If you have high blood pressure, talk with healthcare provider.
• If you have kidney disease, talk with healthcare provider.
• If you have liver disease, talk with healthcare provider.
• If you have had a stroke, talk with healthcare provider.
• If you have a weakened heart, talk with healthcare provider.
• If you are a male and sexually active, protect your partner from pregnancy. Use birth control that you can trust.
• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.
• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• Diarrhea.
• Swelling.
• Breast tenderness.
• Breast enlargement.
• Change in sexual ability or desire. This is usually reversible.
• Leg cramps.
• Heart damage can rarely occur.
• Liver damage can rarely occur.
• Lung damage can rarely occur.
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.
• Chest pain or pressure or fast heartbeat.
• Difficulty breathing.
• Severe nausea or vomiting.
• Severe diarrhea.
• Swelling or pain of leg or arm.
• Severe headache.
• Unusual bruising or bleeding.
• Severe skin irritation.
• Any rash.
• No improvement in condition or feeling worse.
