Created: 2009-04-06 11:55:09.0
Modified: 2010-06-24 10:25:43.0
Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.
• There is a risk of skin cancer. Avoid sun, sunlamps, and tanning beds. Use sunscreen; wear protective clothing and eyewear.
• The risk of cancer is higher after using this medicine.
• If you have diabetes, talk with healthcare provider.
• If you have high cholesterol, talk with healthcare provider.
• If you have liver disease, talk with healthcare provider.
• Tell dentists, surgeons, and other healthcare providers that you use this medicine.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• Do not take St John's wort with this medicine. It may make this medicine less effective.
• Avoid grapefruit and grapefruit juice.
• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.
• Use birth control that you can trust, during treatment, and for 2 months after treatment ends.
• Risk of infection. Avoid people with infections, colds, or flu.
• Anemia, low white blood cell count, and low platelet count.
• High cholesterol level.
• High blood sugar. Usually reverses when stopped.
• High blood pressure.
• Swelling.
• Feeling tired or weak.
• Fever.
• Headache.
• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• Mouth irritation. Frequent mouth care with a soft toothbrush or cotton swabs and rinsing mouth may help.
• Diarrhea.
• Not hungry.
• Lung damage can rarely occur.
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.
• Difficulty breathing.
• Severe belly pain.
• Severe nausea or vomiting.
• Severe diarrhea.
• Unusual bruising or bleeding.
• Severe mouth irritation.
• Severe back pain.
• Blood in the urine.
• Unable to pass urine.
• Skin wound that will not heal.
• Any rash.
• No improvement in condition or feeling worse.
Antineoplastic Agent, mTOR Kinase Inhibitor; Immunosuppressant Agent; mTOR Kinase Inhibitor
• Long-term use may increase risk of cancer and serious infections.
• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.
Zortress®
• A blood clot can occur in your transplanted kidney, call healthcare provider right away if you have back or belly pain, are unable to pass urine, have blood in urine, a fever, nausea or vomiting.
• If you are taking this medicine with cyclosporine you will need a lower dose of cyclosporine, talk with healthcare provider.
• Please read the medication guide.
• If you have an allergy to everolimus, temsirolimus, sirolimus or any other part of this medicine.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
• If you are pregnant or may be pregnant.
• If you are breast-feeding.
• Everolimus injures cancer cells halting their growth.
• It helps the body accept a transplanted organ.
• To gain the most benefit, do not miss doses.
• Take this medicine at a similar time of day.
• Take this medicine with a full glass of water.
• Take this medicine with or without food. Take with food if it causes an upset stomach.
• Swallow whole. Do not chew, break, or crush.
• Take Zortress® at the same time as you take cyclosporine.
• Take a missed dose as soon as possible.
• If it has been 6 hours or more since missed dose, skip the missed dose and return to your regular schedule.
• Do not take a double dose or extra doses.
• Do not change dose or stop medicine. Talk with healthcare provider.
• Change in condition being treated. Is it better, worse, or about the same?
• Check blood work regularly. Talk with healthcare provider.
• Follow up with healthcare provider.
• Store at room temperature.
• Protect from light.
• Protect from moisture. Do not store in a bathroom or kitchen.
• This medicine is used to treat kidney cancer.
• This medicine is used to prevent rejection after organ transplant.
• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
