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Gemtuzumab Ozogamicin Contributions by FoundHealth

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(gem TOO zoo mab oh zog a MY sin)

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Mylotarg®

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Mylotarg®

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Antineoplastic Agent, Monoclonal Antibody

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• Some patients experience severe reactions during the infusion. This medicine causes low blood cell counts for a long period of time. Your healthcare provider will need to monitor your blood cell counts.

• This medicine may cause damage to your liver in certain situations. Talk with healthcare provider.

• This medicine may not be safe if used with other chemotherapy. Talk with healthcare provider.

• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.

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• If you have an allergy to gemtuzumab ozogamicin or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you are pregnant or may be pregnant.

• If you are breast-feeding.

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• Gemtuzumab injures cancer cells causing their death.

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• This medicine is given as a shot into a vein over a period of time.

• Acetaminophen and diphenhydramine will be given 1 hour before this medicine to decrease fever and chills.

• Drink plenty of noncaffeine-containing liquid unless told to drink less liquid by healthcare provider.

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• Call healthcare provider for instructions.

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• Change in condition being treated. Is it better, worse, or about the same?

• Check blood work regularly. Talk with healthcare provider.

• Check weight weekly. Report a weight change to healthcare provider.

• Take good care of your teeth. See a dentist regularly.

• Follow up with healthcare provider.

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• This medicine will be given to you in a healthcare setting. You will not store it at home.

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Created: 2006-10-13 12:50:21.0

Modified: 2010-03-15 13:02:14.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• This medicine is used to treat leukemia.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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What are the precautions when taking this medicine?

• If you have liver disease, talk with healthcare provider.

• If you have lung disease, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Talk with healthcare provider before receiving any vaccinations. Use with this medicine may either increase the risk of serious infection or make the vaccination less effective.

• Tell dentists, surgeons, and other healthcare providers that you use this medicine.

• You may bleed more easily. Be careful. Avoid injury. Use soft toothbrush, electric razor.

• Talk with healthcare provider before using aspirin, aspirin-containing products, other pain medicines, blood thinners, garlic, ginseng, ginkgo, or vitamin E.

• Avoid alcohol (includes wine, beer, and liquor).

• Use birth control that you can trust to prevent pregnancy while taking this medicine.

What are some possible side effects of this medicine?

• Fever and chills while medicine is being given. Medicines may be given to prevent this.

• Risk of infection. Avoid people with infections, colds, or flu.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Diarrhea.

• Not hungry.

• Belly pain.

• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.

• High blood pressure.

• Low blood pressure.

• Swelling.

• Headache.

• Nosebleed.

• Cough.

• Mouth irritation. Frequent mouth care with a soft toothbrush or cotton swabs and rinsing mouth may help.

• Feeling tired or weak.

• Anemia, low white blood cell count, and low platelet count.

• Irritation where the shot is given.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.

• Severe dizziness.

• Severe nausea or vomiting.

• Severe diarrhea.

• Significant weight gain.

• Severe right upper belly pain.

• Unusual bruising or bleeding.

• Yellow skin or eyes.

• Any rash.

• No improvement in condition or feeling worse.

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