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Ixabepilone Contributions by FoundHealth

Article Revisions

Edited Ixabepilone Overview: Overview 14 years ago

(ix ab EP i lone)

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Ixempra®

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Antineoplastic Agent, Antimicrotubular; Antineoplastic Agent, Epothilone B Analog

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• Do not take this medicine with capecitabine if you have severe liver disease. Serious reactions can occur. Talk with healthcare provider.

• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.

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• If you have an allergy to ixabepilone, Cremophor® EL, polyoxyethylated castor oil, or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you have a low platelet count or a low white blood cell count.

• If you have severe liver disease and are taking capecitabine.

• If you are pregnant or may be pregnant.

• If you are breast-feeding.

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• Ixabepilone injures cancer cells causing their death.

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• This medicine is given as a shot into a vein over a period of time.

• Diphenhydramine and other medicine may be given before this medicine to decrease itching.

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• Call healthcare provider for appointment.

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• Change in condition being treated. Is it better, worse, or about the same?

• Check blood work regularly. Talk with healthcare provider.

• Follow up with healthcare provider.

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• This medicine will be given to you in a healthcare setting. You will not store it at home.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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Edited Ixabepilone Overview: 14 years ago

Created: 2007-10-30 17:08:18.0

Modified: 2010-08-03 09:56:43.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• This medicine is used to treat breast cancer.

• This medicine is used to treat endometrial cancer.

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What are the precautions when taking this medicine?

• If you are 65 or older, use this medicine with caution. You could have more side effects.

• If you have diabetes, talk with healthcare provider.

• If you have heart disease, talk with healthcare provider.

• If you have liver disease, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Do not take St John's wort with this medicine. It may make this medicine less effective.

• Talk with healthcare provider before using other: aspirin, aspirin-containing products, blood thinners, garlic, ginseng, ginkgo, ibuprofen or like products, pain medicines, or vitamin E.

• Avoid grapefruit and grapefruit juice.

• Use birth control that you can trust to prevent pregnancy while taking this medicine.

What are some possible side effects of this medicine?

• Low white blood cell count or low platelet count. Medicine may need to be stopped.

• Feeling tired or weak.

• Hair loss. Hair usually grows back when medicine is stopped.

• Headache.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Diarrhea.

• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.

• Belly pain.

• Mouth irritation. Frequent mouth care with a soft toothbrush or cotton swabs and rinsing mouth may help.

• Not hungry.

• Muscle pain.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.

• Difficulty breathing.

• Chest pain or pressure or fast heartbeat.

• Severe nausea or vomiting.

• Severe diarrhea.

• Unusual bruising or bleeding.

• Significant weight gain.

• Dark urine or yellow skin or eyes.

• Feeling extremely tired or weak.

• Numbness or tingling of hands or feet.

• Any rash.

• No improvement in condition or feeling worse.

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