Antineoplastic Agent, Tyrosine Kinase Inhibitor; Epidermal Growth Factor Receptor (EGFR) Inhibitor
• This medicine may cause liver problems. Call healthcare provider if you notice dark urine, feeling tired, not hungry, nausea, vomiting, or yellowing of the skin or eyes.
• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.
• If you have an allergy to lapatinib or any other part of this medicine.
• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
• If you are pregnant or may be pregnant.
• If you are breast-feeding.
• Take this medicine once a day. Do not split up the dose during the day.
• Use prescription as directed, even if feeling better.
• Take this medicine on an empty stomach. Take 1 hour before or 2 hours after meals.
• Swallow tablet whole. Do not chew, break, or crush.
• Take a missed dose as soon as possible.
• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.
• Do not take a double dose or extra doses.
• Do not change dose or stop medicine. Talk with healthcare provider.
• Change in condition being treated. Is it better, worse, or about the same?
• Check blood work. Talk with healthcare provider.
• Follow up with healthcare provider.
• Store at room temperature.
• Protect from moisture. Do not store in a bathroom or kitchen.
Created: 2007-03-16 13:00:10.0
Modified: 2010-03-09 08:29:41.0
Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.
• If you have a life-threatening allergy, wear allergy identification at all times.
• Do not share your medicine with others and do not take anyone else's medicine.
• Keep all medicine out of the reach of children and pets.
• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
• If you have heart disease, talk with healthcare provider.
• If you have liver disease, talk with healthcare provider.
• If you have lung disease, talk with healthcare provider.
• Check medicines with healthcare provider. This medicine may not mix well with other medicines.
• Do not take St John's wort with this medicine. It may make this medicine less effective.
• Talk with healthcare provider before using aspirin, aspirin-containing products, other pain medicines, blood thinners, garlic, ginseng, ginkgo, or vitamin E.
• Avoid grapefruit and grapefruit juice.
• Use birth control that you can trust to prevent pregnancy while taking this medicine.
• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
• Diarrhea.
• Belly pain.
• Skin irritation.
• Headache.
• Hair loss. Hair usually grows back when medicine is stopped.
• Back pain.
• Rash.
• Mouth irritation. Frequent mouth care with a soft toothbrush or cotton swabs and rinsing mouth may help.
• Feeling tired or weak.
• Heart damage can rarely occur.
• Liver damage can rarely occur.
• If you suspect an overdose, call your local poison control center or emergency department immediately.
• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
• Signs or symptoms of infection. These include a fever of 100.5 degrees or higher, chills, severe sore throat, ear or sinus pain, cough, increased sputum or change in color, painful urination, mouth sores, wound that will not heal, or anal itching or pain.
• Difficulty breathing.
• Fast heartbeat.
• Severe dizziness or passing out.
• Severe belly pain.
• Severe nausea or vomiting.
• Severe diarrhea.
• Feeling extremely tired or weak.
• Unusual bruising or bleeding.
• Dark urine or yellow skin or eyes.
• Not able to eat.
• Any rash.
• No improvement in condition or feeling worse.
