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Leuprolide Contributions by FoundHealth

Article Revisions

Edited Leuprolide Overview: Overview 14 years ago

(loo PROE lide)

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Eligard®; Lupron Depot-Ped®; Lupron Depot®; Lupron®

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Eligard®; Lupron®; Lupron® Depot®

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Lorelin; Lucrin Depot; Prelar Depot

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Antineoplastic Agent, Gonadotropin-Releasing Hormone Agonist; Gonadotropin Releasing Hormone Agonist

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• If you have an allergy to leuprolide or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you have undiagnosed vaginal bleeding.

• If you are pregnant or may be pregnant.

• If you are breast-feeding.

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• Leuprolide slows prostate cancer growth by lowering testosterone levels.

• It decreases estrogen levels in females.

• It decreases testosterone levels in males.

• It prevents the eggs from being released too early. This gives the eggs more time to grow.

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• This medicine is given as a shot into the fatty part of the skin or a muscle.

• Your healthcare provider may teach you how to give the shot.

• Wash hands before and after use.

• Throw away needles in needle/sharp disposal box and return box to healthcare provider when full.

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• Call healthcare provider for instructions.

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• Change in condition being treated. Is it better, worse, or about the same?

• Check blood work regularly. Talk with healthcare provider.

• Bone density test.

• Follow up with healthcare provider.

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Eligard®, Lupron Depot-Ped®, Lupron Depot®, Viadur®:

• This medicine will be given to you in a healthcare setting. You will not store it at home.

Lupron®:

• If given at home, may store unopened vials at room temperature or in a refrigerator. Do not freeze.

• Protect from light.

• Protect from heat.

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Edited Leuprolide Overview: 14 years ago

Created: 2005-04-07 16:53:48.0

Modified: 2010-03-09 08:22:24.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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• This medicine is used to treat endometriosis.

• This medicine is used to treat anemia caused by fibroids of the uterus.

• This medicine is used to treat prostate cancer.

• This medicine is used to delay puberty in children who are developing too early.

• This medicine is used to help you get pregnant.

• This medicine is used to treat breast cancer.

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What are the precautions when taking this medicine?

• Disease symptoms may worsen before improving.

• If you have mental illness, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Birth control pills and other hormone-based birth control may not work to prevent pregnancy. Use another form of birth control while taking this medicine.

What are some possible side effects of this medicine?

• Flushing. Wearing layers of clothes or summer clothes and cool environment may help.

• Increased bone pain, blood in urine, and difficulty urinating. Usually resolved 1-2 weeks after treatment has started.

• Weakened bones with long-term use.

• Swelling.

• Headache.

• Feeling tired or weak.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Depression.

• Mood changes.

• Inability to sleep.

• Short-term vaginal bleeding.

• Change in sexual ability or desire. This is usually reversible.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of depression, suicidal thoughts, nervousness, emotional ups and downs, abnormal thinking, anxiety, or lack of interest in life.

• Significant change in thinking clearly and logically.

• Severe behavioral problems.

• Severe headache.

• Severe nausea or vomiting.

• Swelling or pain of leg or arm.

• Increased bone pain after 2-4 weeks of treatment.

• Severe back pain.

• Feeling extremely tired or weak.

• Unable to pass urine.

• Sudden change in vision.

• Vaginal bleeding for more than 2 months.

• Severe skin irritation.

• Any rash.

• No improvement in condition or feeling worse.

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