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Linezolid Contributions by FoundHealth

Article Revisions

Edited Linezolid Overview: Overview 14 years ago

(li NE zoh lid)

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Zyvox®

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Zyvoxam®

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Zyvoxam

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Antibiotic, Oxazolidinone

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• Linezolid may cause anemia, low white blood cell counts, low platelet counts, or may decrease production of all cells made in the bone marrow. Complete blood counts should be done weekly while on this medicine.

• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.

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• If you have an allergy to linezolid or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you have uncontrolled high blood pressure.

• If you have taken isocarboxazid, phenelzine, or tranylcypromine in the last 14 days. Monoamine oxidase inhibitors (eg, isocarboxazid, phenelzine, and tranylcypromine) must be stopped 14 days before this medicine is started. Taking the two together could cause dangerously high blood pressure.

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• Linezolid works to injure the bacteria and fight the infection.

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• To gain the most benefit, do not miss doses.

• Use prescription as directed, even if feeling better.

• Take this medicine with or without food. Take with food if it causes an upset stomach.

• Follow diet instructions. Certain foods and drinks taken with this medicine can cause very dangerous reactions such as sudden high blood pressure. To prevent these problems, get a list of foods to avoid from a nutritionist.

• Avoid eating aged cheeses and meats, soy sauce, soy bean including paste, Miso soup, Italian green beans (fava beans), snowpea or broad bean pods, sauerkraut, kimchee, concentrated yeast extracts (Marmite), red or white wine, and beer including alcohol-free beer.

• If medicine is stopped, follow diet for at least 2 more weeks.

• A liquid (suspension) is available if you cannot swallow pills. Gently mix before use. Do not shake.

• Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after medicine is given.

Injection:

• This medicine is given as a shot into a vein over a period of time.

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• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

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• Change in condition being treated. Is it better, worse, or about the same?

• Check blood pressure and heart rate regularly if you have heart disease.

• Check blood work regularly. Talk with healthcare provider.

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• Store at room temperature.

• Protect from light.

• Protect tablets from moisture. Do not store in a bathroom or kitchen.

• Store liquid (suspension) at room temperature. Throw away any unused portion after 3 weeks.

• Follow directions for storage of injection. Talk with healthcare provider.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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Edited Linezolid Overview: 14 years ago

Created: 2006-10-13 13:39:53.0

Modified: 2010-05-05 15:41:31.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• This medicine is used to treat a variety of bacterial infections.

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What are the precautions when taking this medicine?

• If you have high blood pressure, talk with healthcare provider.

• If you have an overactive thyroid, talk with healthcare provider.

• If you have PKU, talk with healthcare provider. Some products do contain phenylalanine.

• If you have seizures, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• If you are taking this medicine and have high blood pressure, talk with healthcare provider before using over-the-counter products that may increase blood pressure. These include cough or cold remedies, diet pills, stimulants, ibuprofen or like products, and certain natural products or supplements.

• Tell healthcare provider if you are pregnant or plan on getting pregnant.

• Tell healthcare provider if you are breast-feeding.

What are some possible side effects of this medicine?

• Anemia, low white blood cell count, and low platelet count can rarely occur.

• Headache.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Diarrhea. Yogurt, Bifidobacterium bifidum, or Lactobacillus acidophilusmay help. These products are available at health food stores or in some pharmacies.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Difficulty breathing.

• Severe headache.

• Severe nausea or vomiting.

• Severe diarrhea, even after medicine is stopped.

• Severe dizziness or passing out.

• Unusual bruising or bleeding.

• Feeling extremely tired or weak.

• Sudden change in vision.

• Any rash.

• No improvement in condition or feeling worse.

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