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Mefloquine Contributions by FoundHealth

Article Revisions

Edited Mefloquine Overview: Overview 14 years ago

(ME floe kwin)

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Lariam® [DSC]

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Apo-Mefloquine®; Lariam®

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Antimalarial Agent

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• This medicine does not mix well with many medicines. Serious reactions may occur. Check all medicines with healthcare provider.

• Please read the medication guide.

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• If you have an allergy to mefloquine or any other part of this medicine.

• If you have an allergy to quinidine or quinine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you have any of the following conditions: Anxiety, depression, psychosis, or seizures.

• If you are pregnant or may be pregnant.

• If you are breast-feeding.

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• Mefloquine protects you from getting malaria.

• It works to injure the bacteria and fight the infection.

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• This medicine should be started before travel to the high risk area. Continue use after leaving the area.

• To gain the most benefit, do not miss doses.

• Use prescription as directed, to prevent malaria.

• Take this medicine with food.

• Take this medicine with a full glass of water.

• To treat malaria, take a single dose. To prevent recurrence of infection, take this medicine with another antibiotic.

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• Take a missed dose as soon as possible.

• If you miss a dose before leaving for your trip, call healthcare provider for instructions.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

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• Change in condition being treated. Is it better, worse, or about the same?

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• Store at room temperature.

• Protect from moisture. Do not store in a bathroom or kitchen.

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Edited Mefloquine Overview: 14 years ago

Created: 2006-10-13 14:00:49.0

Modified: 2010-03-22 09:50:51.0

Lexi-PALS TM © (1977)-(2007) Lexi-Comp, Inc. All rights reserved.

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• This medicine is used to prevent or treat malaria.

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• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

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What are the precautions when taking this medicine?

• Have patient safety card with you at all times.

• If you have liver disease, talk with healthcare provider.

• If you have heart disease, talk with healthcare provider.

• Other protective measures are needed along with this medicine including using screens, bednetting, insect repellent (10% to 35% DEET), and permethrin spray on clothing and nets. Avoid spraying most insect repellents on children. Decrease evening and night-time outdoor activity.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.

• Avoid alcohol (includes wine, beer, and liquor) or other medicines and natural products that slow your actions and reactions.

• Avoid grapefruit and grapefruit juice.

• Use birth control that you can trust to prevent pregnancy while taking this medicine.

What are some possible side effects of this medicine?

Treatment of malaria:

• Headache.

• Feeling lightheaded, sleepy, having blurred vision, or a change in thinking clearly. Avoid driving, doing other tasks or activities that require you to be alert or have clear vision until you see how this medicine affects you.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

Prevention of malaria:

• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.

• Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Hallucinations.

• Inability to sleep.

• Bad dreams.

• Psychosis can rarely occur.

• Seizures can rarely occur.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Signs or symptoms of depression, suicidal thoughts, nervousness, emotional ups and downs, abnormal thinking, anxiety, or lack of interest in life.

• Chest pain or pressure or fast heartbeat.

• Severe dizziness or passing out.

• Difficulty breathing.

• Flu-like symptoms.

• Very nervous and excitable.

• Severe nausea or vomiting.

• Significant change in thinking clearly and logically.

• Any rash.

• No improvement in condition or feeling worse.

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